HFMD 101: The Fast Facts
Hand‑Foot‑and‑Mouth disease (HFMD) is a mild but highly contagious viral rash caused most often by coxsackievirus A16 or enterovirus 71 (CDC). It strikes children under 5, shows up as blisters on the palms, soles, and mouth, and usually clears in 7–10 days without complications.
Contagion Timeline at a Glance
Phase | Day Range | What’s Happening | Contagious Level |
Incubation | 3 – 6 days | Virus multiplies silently | — |
Prodrome | Day 0 | Low‑grade fever, sore throat | High |
Full rash | Days 1 – 4 | Mouth ulcers, hand/foot blisters | Highest (first week) (CDC) |
Recovery | Days 5 – 10 | Scabs heal, appetite returns | Moderate—virus still in stool |
Shedding | Up to 4 weeks | Virus exits in poop | Low but present |
Return‑to‑school rule: Fever‑free 24 hrs and mouth sores improving, even if spots remain on skin (Seattle Children’s Hospital).
Symptom Checklist (0 – 10 Days)
System | Common Signs |
Skin | Flat red spots → gray blisters on palms, soles, buttocks |
Mouth | Painful ulcers on tongue, gums, cheeks |
General | Fever 100–102 °F, poor appetite, crankiness |
GI | Occasional loose stools or nausea |
If your child develops neck stiffness, constant vomiting, or a rash that spreads beyond classic zones, call your doctor—rare enterovirus strains can trigger meningitis (CDC).
Home‑Care Toolkit
Tool | Dose / How Often | Why It Helps |
Acetaminophen | 15 mg/kg q4–6 hrs | Lowers fever, mouth‑ulcer pain |
Cold foods | Ice pops, smoothies | Numbs mouth sores, boosts fluids |
Magic mouthwash (Rx) | Swish 30 sec before meals | Coats ulcers for pain‑free eating |
Hydrogel hand spray | 3× daily on blisters | Soothes itch, speeds drying |
ORS | 30–60 ml after each loose stool | Prevents dehydration |
Skip ibuprofen if mouth intake is poor; empty stomach plus NSAIDs = higher ulcer pain. Never pop blisters—fluid is loaded with virus.
Comfort Menu (24‑Hour Plan)
Meal | HFMD‑Friendly Choice | Avoid |
Breakfast | Greek yogurt + honey (if > 12 mo) | Citrus juice |
Snack | Frozen banana bites | Salty chips |
Lunch | Lukewarm oatmeal | Spicy soup |
Snack | Watermelon cubes (cold) | Tomatoes |
Dinner | Scrambled eggs, mashed potatoes | Acidic marinara |
Cleaning & Isolation Hacks
- Bleach it: 1 Tbsp bleach : 1 gal water on toys & counters—alcohol wipes don’t kill enterovirus.
- Toy quarantine: Seal stuffed animals for 3 days; virus dies without a host.
- Separate towels: Use color‑coded hand towels for sick kids.
- Hand‑wash drills: 20‑second soap scrub after diaper changes—virus sheds in stool for weeks (CDC).
Myth‑Busting Corner
Myth | Reality |
“Antibiotics clear the rash.” | HFMD is viral; antibiotics do nothing. |
“Once spots are scabbed, we’re safe.” | Virus can still shed in poop for 4 weeks. |
“Adult caregivers won’t catch it.” | Grown‑ups can get mild or no symptoms but still spread virus. |
OTC vs Prescription Decision Tree
- Is your child refusing fluids for 8+ hrs?
Yes ➜ Call clinic for ondansetron melt and IV‑fluid check. - Mouth pain ≥ 4/10 despite acetaminophen?
Yes ➜ Ask about lidocaine/maalox swish (magic mouthwash). - Itch disrupts sleep?
Yes ➜ Discuss hydroxyzine nighttime dose.
Book a quick rash assessment if you need any of the above.
Preventing Household Spread
Action | Effectiveness |
Hand‑washing after diaper duty | ⭐⭐⭐⭐⭐ |
Disinfect phone screens daily | ⭐⭐⭐⭐ |
No shared cups, even siblings | ⭐⭐⭐⭐ |
Teach “dab‑sneeze” into elbow | ⭐⭐⭐ |
Parents: wash hands before touching your face—adults often forget this step and become silent carriers.
Return‑to‑Play Guidelines
Activity | When It’s Safe |
Day‑care / school | Fever‑free 24 hrs + eating normally |
Swim lessons | After blisters scab (≈ 7 days) to protect others |
Contact sports | Same as swim—avoid popped blisters snagging |
Grandparent visits | Wait until mouth sores healed; seniors weaker immunity |
Sample 3‑Day Recovery Log
Time | Temp °F | Fluids oz | Blisters Count | Pain (0‑3) | Notes |
Day 1 AM | 101.3 | 4 | 15 | 3 | Started acetaminophen |
Day 1 PM | 100.2 | 10 | 25 | 2 | Added ORS |
Day 2 AM | 99.4 | 12 | 28 (drying) | 1 | Eating yogurt |
Day 3 AM | 98.7 | 16 | 30 (scabbed) | 0 | Fever‑free 24 hrs |
Bring this chart to follow‑up; trends guide clearance decisions.
When to Head to the ER
- < 6 wet diapers in 24 hrs or sunken fontanelle
- Fever > 103 °F unresponsive to meds
- Blisters spreading to eyes or genitals
- Weak cry, little movement, or confusion
- Rapid breathing or mottled skin
External Resources Worth Bookmarking
- HFMD Parent FAQ – CDC (signs, spread, cleaning tips).
- Seattle Children’s HFMD Care Sheet (return‑to‑school guidance).
Both open in new tabs for easy midnight reference.
Quick‑Fire Parent Q&A
Q: Can I breastfeed if I have HFMD?
A: Yes—virus hasn’t been found in breast milk; antibodies may help baby.
Q: Do gloves help when applying cream?
A: Disposable gloves reduce virus on your hands; toss after one use.
Q: Are epsom‑salt foot soaks OK?
A: Yes, lukewarm soaks ease foot pain; pat dry—no picking scabs.
One‑Minute Recap
- Most contagious first week—isolate but don’t panic.
- Manage pain: acetaminophen + cold foods.
- Push fluids; watch diaper counts.
- Bleach‑based cleaning beats alcohol wipes.
- Blisters healed? Fever gone? Back to school!
Ready for Professional Eyes?
Book a quick rash assessment—our pediatric team confirms HFMD, checks hydration, and emails school‑return notes the same day.